While DNA evidence has been a hot topic regarding the Book of Mormon, another interesting application involves the descendants of Joseph Smith. A recent Deseret News article reports that DNA evidence has been used to rule out the possibility that Joseph Smith was the ancestor for three people suspected of being fathered by Joseph with polygamous wives. Other alleged descendants will be tested later, if all goes well. Thanks to Mike Parker for sharing this story with me.
As for the attacks on the Book of Mormon, see my page on DNA and the Book of Mormon.